FIGURE

Fig. 7

ID

ZDB-FIG-071223-6

Publication

Yabe et al., 2007 - The zebrafish maternal-effect gene cellular atoll encodes the centriolar component sas-6 and defects in its paternal function promote whole genome duplication

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Fig. 7

One-cycle cell division delay in embryos from mutant cea fathers. Live embryos at the indicated time points. (A–F) are side views, (B′, D′) are animal views of the same embryos shown in panels B, D. A fraction of paternally mutant cea embryos show a one-cycle delay in cell division (panel C, compare to panel A), but subsequently resume normal cleavage (D, D′). At 5 days p.f., embryos that undergo a one-cycle delay in cell division (F) exhibit heart edema (asterisk) and lack swim-bladder inflation (arrow). (G, H) Metaphase spreads from 24-h embryos. Wild-type embryos contain a normal complement of 50 chromosomes (G), while paternally mutant cea embryos that experience a one-cell cycle delay in the first cell division contain a duplicated number of chromosomes (H).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sass6^{p37mfa/p37mfa} (AB/TU) sass6^p37mfa/+ (AB/TU)
Observed In:	blastomere centriole replication embryonic cleavage heart sperm centriole swim bladder swim bladder inflation whole organism whole organism chromosome
Stage Range:	2-cell to Adult

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 312(1), Yabe, T., Ge, X., and Pelegri, F., The zebrafish maternal-effect gene cellular atoll encodes the centriolar component sas-6 and defects in its paternal function promote whole genome duplication, 44-60, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.