FIGURE

Fig. 3

ID

ZDB-FIG-070802-30

Publication

Kok et al., 2007 - The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis

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Fig. 3

Somite segmentation and PSM maturation are disrupted in SBU2 mutants. Whole mount RNA in situ hybridization of genes involved in somite segmentation process in wild-type and SBU2 mutants. All views are dorsal; anterior to the top. In wild-type embryos, periodic activation of notch signaling provides cycling gene expression of Notch pathway genes such as her1 and her7 (A–D and E–H). dld expression is weak and diffused in presomitic mesoderm as well as anteriormost somites (I–L). tbx24 normally expressed in intermediate and anterior PSM, is also reduced in SBU2embryos (M–P). Arrows denote stripes of her1, her7 or dld expression.

Expression Data

Genes:	dld her1 her7 tbx6
Fish:	WT supt6h^sbu2/sbu2
Anatomical Terms:	segmental plate somite
Stage Range:	1-4 somites to 10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 307(2), Kok, F.O., Oster, E., Mentzer, L., Hsieh, J.C., Henry, C.A., and Sirotkin, H.I., The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis, 214-226, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.