FIGURE

Fig. 3

ID

ZDB-FIG-070620-3

Publication

Yeyati et al., 2007 - Hsp90 Selectively Modulates Phenotype in Vertebrate Development

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Fig. 3

Assessing Range of Expressivity and Quantifying Phenotype Modulation in sri and dre Strains (A–H) Phenotype of the sri and dre eye mutants at 5 dpf. (A–D) Lateral view of live embryos; (E–H) histological sections. (A) WT; lens (white-dotted lines) and retina (red-dotted lines) measurements were used to asses phenotypic severity; (E) WT section showing retina (re), lens (le), cornea (co); (B) and (F) sri mild and (C) and (G) sri severe; (D) dre with coloboma (cb); (H) dre showing flattened anterior segment. (I and J) Ranked plots showing distribution of quantitative eye parameters in treated (white circles) and sibling control (black circles) homozygous embryos: (I) Ratio of retina to lens area; (J) Lens shape or eccentricity.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pax6b^{tq253a/tq253a} sufu^{tm146d/tm146d}
Condition:	chemical treatment: radicicol
Observed In:	lens lens development in camera-type eye optic cup morphogenesis involved in camera-type eye development
Stage:	Day 5

Phenotype Detail

Acknowledgments

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