FIGURE

Fig. 5

ID

ZDB-FIG-070307-66

Publication

Hultman et al., 2007 - Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a

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Fig. 5

kitla Morphant Phenocopies kita^b5 Survival Phenotype (A) Wild-type larva at 8 dpf. (B) Higher magnification of dorsal melanocyte stripe of 8 dpf wild-type larva with healthy melanocytes (black arrowhead). (C) kitla MO shows fewer melanocytes at 8 dpf, similar to kita^b5. (D) Higher magnification of kitla MO showing melanocytes blebbing through the skin (red arrow), characteristic of melanocyte programmed cell death. (E and F) kitlb MO at 8 dpf (E) and higher magnification (F) of kitlb MO 8 dpf, which is indistinguishable from wild-type. (G) Total melanocyte counts show that the survival phenotypes of kita^b5 and kitla MO are similar. Scale bars: 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kita^b5/b5 WT + MO1-kitlga WT + MO1-kitlgb
Knockdown Reagents:	MO1-kitlga MO1-kitlgb
Observed In:	melanocyte
Stage Range:	Day 4 to Days 7-13

Phenotype Detail

Acknowledgments

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