FIGURE

Fig. 8

ID

ZDB-FIG-070214-5

Publication

Zecchin et al., 2007 - Distinct delta and jagged genes control sequential segregation of pancreatic cell types from precursor pools in zebrafish

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Fig. 8

Expression of insulin, somatostatin (PPSS2), glucagon, pax6.2 and pdx1 in ins:Gal4;UAS:N^ICD bi-genic embryos. Mono-genic control embryos (ins:Gal4 neg and UAS:N^ICD pos) are on the left and bi-genic embryos (ins:Gal4 pos and UAS:N^ICD pos) are on the right. Expression of N^ICD under the control of the insulin promoter leads to the lack of insulin-producing cells but somatostatin and glucagon producing cells are present similarly to control. Genes whose expression is analyzed are indicated on the left while the genotypes are indicated on the top. Embryos are in ventral views with anterior to the left. Individual embryos were genotyped by PCR for presence or absence of each transgene. Scale bar is 50 μm.

Expression Data

Genes:	gcga ins pax6b pdx1 sst2
Fish:	kca3Tg/+; m1080Tg/+ kca3Tg/+; m1080Tg/m1080Tg
Anatomical Terms:	pancreas primordium pancreatic bud
Stage Range:	20-25 somites to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 301(1), Zecchin, E., Filippi, A., Biemar, F., Tiso, N., Pauls, S., Ellertsdottir, E., Gnugge, L., Bortolussi, M., Driever, W., and Argenton, F., Distinct delta and jagged genes control sequential segregation of pancreatic cell types from precursor pools in zebrafish, 192-204, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.