FIGURE

Fig. 7

ID

ZDB-FIG-070126-7

Publication

Lee et al., 2006 - Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud

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Fig. 7

Blimp-1 function is necessary for shh expression whereas Hh signaling is required for maintenance, but not the initiation, of blimp-1 expression. (A-F) shh expression (arrows) in the ZPA of wild-type, ubo mutant and a blimp-1 morphant embryos at specific developmental stages. (G-I) blimp-1 expression (arrows) in embryos lacking Shh activity. (J-L) blimp-1 expression (arrows) in embryos lacking Smo activity. Panels A-F, G and J depict dorsal views; panels H, I, K and L show lateral views.

Expression Data

Genes:	prdm1a shha
Fish:	Df(Chr07)t4/t4 WT WT + MO2-prdm1a prdm1a^tp39 smo^b641
Knockdown Reagent:	MO2-prdm1a
Anatomical Terms:	mesenchyme pectoral fin pectoral fin pectoral fin bud zone of polarizing activity pectoral fin bud
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 300(2), Lee, B.C., and Roy, S., Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud, 623-634, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.