FIGURE

Fig. 6

ID

ZDB-FIG-060828-5

Publication

Eaton et al., 2006 - The zebrafish bHLH PAS transcriptional regulator, single-minded 1 (sim1), is required for isotocin cell development

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Fig. 6

Sim1 is required for itnp mRNA expression. Itnp and sim1 mRNA was detected by ISHH in embryos that were injected with Morpholino oligonucleotides (MO). A,C,E: Embryos injected with 0.5 ng of a 4-base mismatch "control" sim1 MO. B,D,F: Embryos injected with 0.5 ng of sim1 MO (e.g., sim1 morphants, MO^sim1). A, B, E, and F are lateral views, dorsal is up and anterior to the left. C and D are ventral views, anterior is up. The probes are indicated on each panel. A,C: The location of the itnp expression domain is indicated with a white arrowhead. The location of the optic recess (or) is indicated by a black bar. t, telencephalon; m, midbrain; hy, hypothalamus.

Expression Data

Genes:	oxt sim1a
Fish:	WT + MO1-sim1a
Knockdown Reagent:	MO1-sim1a
Anatomical Terms:	diencephalon hypothalamus telencephalon
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-sim1a
Knockdown Reagent:	MO1-sim1a
Observed In:	embryo development eye head
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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