FIGURE

Fig. 5

ID

ZDB-FIG-050308-6

Publication

Tay et al., 2005 - A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo

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Fig. 5

Inactivation of Cos2 function induces ectopic Hh signalling in the ventral neural tube. (A) fkd4 expression in the ventral neural tube (MFP and LFP cells) of a 22-somite stage wild-type embryo. (B) Upregulation of the levels and expansion in the domain of fkd4 expression in the ventral neural tube of a 22-somite stage cos2 morphant (n=16/22). (C) Expression pattern of fkd4 in ventral cell populations of the developing mid- and hindbrain of a 22-somite stage wild-type embryo. (D) Increased levels and enlargement of the domain of fkd4 in ventral cell populations of the developing mid- and hindbrain of a 22-somite stage cos2 morphant embryo (n=13/22).

Expression Data

Gene:	foxa
Fish:	WT WT + MO1-kif7 + MO2-kif7
Knockdown Reagents:	MO1-kif7 MO2-kif7
Anatomical Terms:	hindbrain midbrain neural tube
Stage:	20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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