CRISPR

CRISPR6-socs3b

ID

ZDB-CRISPR-240430-2

Name

CRISPR6-socs3b

Previous Names

None

Target

socs3b (1)

Sequence

5' - GTCCGAGCTGTCCCGCACC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mdu24	socs3b

Expression

Gene expression in Wild Types + CRISPR6-socs3b

No data available

Phenotype

Phenotype resulting from CRISPR6-socs3b

No data available

Phenotype of all Fish created by or utilizing CRISPR6-socs3b

Phenotype	Fish	Conditions	Figures
whole organism tgfb1b expression increased amount, abnormal	socs3b^mdu24/mdu24	ablation: caudal fin	Figure 5 from Sobah et al., 2023
eye il1b expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 7 from Sobah et al., 2023
whole organism il6 expression increased amount, abnormal	socs3b^mdu24/mdu24	ablation: caudal fin	Figure 5 from Sobah et al., 2023
eye tnfa expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 7 from Sobah et al., 2023
eye il4 expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 7 from Sobah et al., 2023
neutrophil mpx expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 2 , Figure 3 from Sobah et al., 2023
whole organism cxcl8a expression increased amount, abnormal	socs3b^mdu24/mdu24	ablation: caudal fin	Figure 5 from Sobah et al., 2023
whole organism cxcr3.2 expression increased amount, abnormal	socs3b^mdu24/mdu24	ablation: caudal fin	Figure 5 from Sobah et al., 2023
leukocyte lcp1 expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 3 from Sobah et al., 2023
whole organism ccr2 expression increased amount, abnormal	socs3b^mdu24/mdu24	ablation: caudal fin	Figure 5 from Sobah et al., 2023
whole organism decreased length, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 6 from Sobah et al., 2023
eye cxcr3.2 expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 7 from Sobah et al., 2023
leukocyte csf3r expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 3 from Sobah et al., 2023
whole organism il1b expression increased amount, abnormal	socs3b^mdu24/mdu24	ablation: caudal fin	Figure 5 from Sobah et al., 2023
eye il6 expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 7 from Sobah et al., 2023
eye il21 expression increased amount, abnormal	socs3b^mdu24/mdu24	standard conditions	Figure 7 from Sobah et al., 2023
eye macrophage increased amount, abnormal	socs3b^mdu24/mdu24; gl22Tg/gl22Tg	standard conditions	Figure 7 from Sobah et al., 2023
kidney macrophage decreased amount, abnormal	socs3b^mdu24/mdu24; gl22Tg/gl22Tg	standard conditions	Figure 6 from Sobah et al., 2023
macrophage wound healing involved in inflammatory response increased process quality, abnormal	socs3b^mdu24/mdu24; gl22Tg/gl22Tg	ablation: caudal fin	Figure 5 from Sobah et al., 2023
whole organism mpx expression increased amount, abnormal	socs3b^mdu24/mdu24; gl22Tg/gl22Tg	standard conditions	Figure 6 from Sobah et al., 2023
whole organism semi-viable, abnormal	socs3b^mdu24/mdu24; gl22Tg/gl22Tg	standard conditions	Figure 7 from Sobah et al., 2023
neutrophil increased amount, exacerbated	socs3b^mdu24/mdu24; i114Tg/i114Tg	chemical treatment by environment: lipopolysaccharide	Figure 4 from Sobah et al., 2023
neutrophil EGFP expression increased amount, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	standard conditions	Figure 3 , Figure 4 from Sobah et al., 2023
kidney neutrophil increased amount, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	standard conditions	Figure 6 from Sobah et al., 2023
eye neutrophil increased amount, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	standard conditions	Figure 7 from Sobah et al., 2023
neutrophil wound healing involved in inflammatory response decreased process quality, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	ablation: caudal fin	Figure 5 from Sobah et al., 2023
whole organism mpx expression increased amount, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	standard conditions	Figure 6 from Sobah et al., 2023
neutrophil increased amount, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	standard conditions	Figure 4 from Sobah et al., 2023
neutrophil EGFP expression increased amount, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	chemical treatment by environment: lipopolysaccharide	Figure 4 from Sobah et al., 2023
whole organism semi-viable, abnormal	socs3b^mdu24/mdu24; i114Tg/i114Tg	standard conditions	Figure 7 from Sobah et al., 2023

Citations