CRISPR

CRISPR6-tln1

ID
ZDB-CRISPR-240212-1
Name
CRISPR6-tln1
Previous Names
None
Target
Sequence
5' - GGGCGGACGCTGCGGGAGC - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
uq1al tln1
Expression
Gene expression in Wild Types + CRISPR6-tln1
No data available
Phenotype
Phenotype resulting from CRISPR6-tln1
No data available
Phenotype of all Fish created by or utilizing CRISPR6-tln1
Phenotype Fish Conditions Figures
whole organism tln1 expression absent, abnormal tln1uq1al/uq1al standard conditions Fig. 1 with image from Chau et al., 2022
cranial vasculature hemorrhagic, abnormal tln1uq1al/uq1al standard conditions Fig. 1 with image from Chau et al., 2022
dorsal aorta focal adhesion assembly decreased process quality, abnormal tln1uq1al/uq1al; uq2alTg standard conditions Fig. 1 with image from Chau et al., 2022
dorsal aorta cell-cell junction EGFP expression spatial pattern, abnormal tln1uq1al/uq1al; uq2alTg standard conditions Fig. 1 with image from Chau et al., 2022
dorsal aorta focal adhesion EGFP expression decreased amount, abnormal tln1uq1al/uq1al; uq2alTg standard conditions Fig. 1 with image from Chau et al., 2022
blood vessel endothelial cell focal adhesion assembly decreased process quality, abnormal tln1uq1al/uq1al; uq2alTg standard conditions Fig. 1 with image from Chau et al., 2022
blood vessel endothelial cell regulation of actin filament organization process quality, ameliorated tln1uq1al/uq1al; uq3alTg chemical treatment by environment: jaspamide Fig. 6 with image from Chau et al., 2022
blood vessel endothelial cell regulation of actin filament organization decreased process quality, abnormal tln1uq1al/uq1al; uq3alTg standard conditions Fig. 5 with imageFig. 6 with image from Chau et al., 2022
dorsal longitudinal anastomotic vessel vascular plexus decreased branchiness, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 2 with image from Chau et al., 2022
dorsal aorta cell-cell junction irregularly shaped, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 3 with imageFig. 6 with image from Chau et al., 2022
intersegmental vessel angiogenic sprout decreased length, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 2 with image from Chau et al., 2022
intersegmental vessel dissociated from dorsal longitudinal anastomotic vessel, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 2 with image from Chau et al., 2022
intersegmental vessel has fewer parts of type intersegmental vessel blood vessel endothelial cell, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 3 with image from Chau et al., 2022
dorsal aorta blood vessel endothelial cell shape, ameliorated tln1uq1al/uq1al; uq11bhTg chemical treatment by environment: jaspamide Fig. 6 with image from Chau et al., 2022
dorsal aorta cell-cell junction shape, ameliorated tln1uq1al/uq1al; uq11bhTg chemical treatment by environment: jaspamide Fig. 6 with image from Chau et al., 2022
intersegmental vessel blood vessel endothelial cell shortened, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 3 with image from Chau et al., 2022
dorsal aorta blood vessel endothelial cell shortened, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 3 with imageFig. 6 with image from Chau et al., 2022
intersegmental vessel sprouting angiogenesis decreased process quality, abnormal tln1uq1al/uq1al; uq11bhTg standard conditions Fig. 2 with image from Chau et al., 2022
intersegmental vessel regulation of filopodium assembly decreased process quality, abnormal tln1uq1al/uq1al; s916Tg standard conditions Fig. 2 with image from Chau et al., 2022
intersegmental vessel sprouting angiogenesis decreased process quality, abnormal tln1uq1al/uq1al; s916Tg standard conditions Fig. 2 with image from Chau et al., 2022
Citations