CRISPR

CRISPR1-acvr2bb

ID

ZDB-CRISPR-231213-16

Name

CRISPR1-acvr2bb

Previous Names

None

Target

acvr2bb (1)

Sequence

5' - ACGAGGCACCAACCTTCAGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "TGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

No data available

Expression

Gene expression in Wild Types + CRISPR1-acvr2bb

No data available

Phenotype

Phenotype resulting from CRISPR1-acvr2bb

No data available

Phenotype of all Fish created by or utilizing CRISPR1-acvr2bb

Phenotype	Fish	Conditions	Figures
whole organism dorsalized, abnormal	acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
eye decreased size, abnormal	acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
caudal fin curled, abnormal	acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
extension increased thickness, abnormal	acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
eye decreased size, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285} + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
caudal fin curled, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285} + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
extension increased thickness, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285} + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
whole organism dorsalized, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
eye decreased size, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
caudal fin curled, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
extension increased thickness, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
whole organism dorsalized, abnormal	acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
extension increased thickness, abnormal	acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
eye decreased size, abnormal	acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
caudal fin curled, abnormal	acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
whole organism dorsalized, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
extension increased thickness, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
margin Ab9-smad2 labeling increased amount, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
eye decreased size, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
caudal fin curled, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022
margin nodal signaling pathway increased rate of occurrence, abnormal	acvr2aa^{sa34654/sa34654}; acvr2ab^{sa18285/sa18285}; acvr2ba^t08pm/t08pm + CRISPR1-acvr2bb + CRISPR2-acvr2bb + CRISPR3-acvr2bb	standard conditions	Figure 2 from Preiß et al., 2022

Citations