Gene
acvr2bb
- ID
- ZDB-GENE-170621-5
- Name
- activin A receptor type 2Bb
- Symbol
- acvr2bb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to have ATP binding activity; metal ion binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to localize to integral component of membrane.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Preiß et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| visceral heterotaxy | Alliance | Heterotaxy, visceral, 4, autosomal | 613751 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000472 | Activin types I and II receptor domain |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR000333 | Ser/Thr protein kinase, TGFB receptor |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR045860 | Snake toxin-like superfamily |
Domain Details Per Protein
| Protein | Length | Activin types I and II receptor domain | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Ser/Thr protein kinase, TGFB receptor | Snake toxin-like superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0G2KN81
|
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available