CRISPR

CRISPR1-abcc2

ID

ZDB-CRISPR-210409-2

Name

CRISPR1-abcc2

Previous Names

None

Target

Sequence

5' - GGTGGCGTTCGTGCAGTCGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "TGG" at the 3' end

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3512	abcc2

Expression

Gene expression in Wild Types + CRISPR1-abcc2

No data available

Phenotype

Phenotype resulting from CRISPR1-abcc2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-abcc2

Phenotype	Fish	Conditions	Figures
gall bladder morphology, ameliorated	abcc2^{zf3512/zf3512}	chemical treatment by environment: biliatresone, chemical treatment by environment: N-acetyl-L-cysteine	Fig. 2 from Zhao et al., 2020
intrahepatic bile duct hypoplastic, ameliorated	abcc2^{zf3512/zf3512}	chemical treatment by environment: biliatresone, chemical treatment by environment: N-acetyl-L-cysteine	Fig. 2 from Zhao et al., 2020
gall bladder damaged, abnormal	abcc2^{zf3512/zf3512}	chemical treatment by environment: biliatresone	Fig. 2 from Zhao et al., 2020
intrahepatic bile duct hypoplastic, abnormal	abcc2^{zf3512/zf3512}	chemical treatment by environment: biliatresone	Fig. 2 from Zhao et al., 2020
intrahepatic bile duct hypoplastic, abnormal	abcc2^zf3512/+	chemical treatment by environment: biliatresone	Fig. 2 from Zhao et al., 2020
gall bladder damaged, abnormal	abcc2^zf3512/+	chemical treatment by environment: biliatresone	Fig. 2 from Zhao et al., 2020
cholangiocyte cell redox homeostasis disrupted, abnormal	abcc2^{zf3512/zf3512}; zf2123Tg; zf3510Tg	standard conditions	Fig. 1 from Zhao et al., 2020

Citations