CRISPR

CRISPR1-gclm

ID

ZDB-CRISPR-210409-1

Name

CRISPR1-gclm

Previous Names

None

Target

Sequence

5' - GGAATTTAGTGAACCGCAGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "CGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zf3511	gclm

Expression

Gene expression in Wild Types + CRISPR1-gclm

No data available

Phenotype

Phenotype resulting from CRISPR1-gclm

No data available

Phenotype of all Fish created by or utilizing CRISPR1-gclm

Phenotype	Fish	Conditions	Figures
intrahepatic bile duct hypoplastic, abnormal	gclm^{zf3511/zf3511}	chemical treatment by environment: biliatresone, chemical treatment by environment: N-acetyl-L-cysteine	Fig. 2 from Zhao et al., 2020
gall bladder damaged, abnormal	gclm^{zf3511/zf3511}	chemical treatment by environment: biliatresone	Fig. 2 from Zhao et al., 2020
gall bladder damaged, abnormal	gclm^{zf3511/zf3511}	chemical treatment by environment: biliatresone, chemical treatment by environment: N-acetyl-L-cysteine	Fig. 2 from Zhao et al., 2020
intrahepatic bile duct hypoplastic, abnormal	gclm^{zf3511/zf3511}	chemical treatment by environment: biliatresone	Fig. 2 from Zhao et al., 2020
hepatocyte cell redox homeostasis disrupted, abnormal	gclm^{zf3511/zf3511}; zf2123Tg; zf3510Tg	standard conditions	Fig. 1 from Zhao et al., 2020
cholangiocyte cell redox homeostasis disrupted, abnormal	gclm^{zf3511/zf3511}; zf2123Tg; zf3510Tg	standard conditions	Fig. 1 from Zhao et al., 2020

Citations