CRISPR

CRISPR2-pax6a

ID

ZDB-CRISPR-210322-3

Name

CRISPR2-pax6a

Previous Names

None

Target

Sequence

5' - GGTCTGGCTGGGCTGTGAAG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ka709	pax6a

Expression

Gene expression in Wild Types + CRISPR2-pax6a

No data available

Phenotype

Phenotype resulting from CRISPR2-pax6a

No data available

Phenotype of all Fish created by or utilizing CRISPR2-pax6a

Phenotype	Fish	Conditions	Figures
lens decreased size, abnormal	pax6a^ka709/ka709	standard conditions	Fig 6 from Takamiya et al., 2020
eye decreased size, abnormal	pax6a^ka709/ka709	standard conditions	Fig 6 from Takamiya et al., 2020
eye ephb3a expression absent, abnormal	pax6b^{tq253a/tq253a}; pax6a^ka709/ka709	standard conditions	Fig 8 from Takamiya et al., 2020
solid lens vesicle cryba4 expression decreased amount, abnormal	pax6b^{tq253a/tq253a}; pax6a^ka709/ka709	standard conditions	Fig 8 from Takamiya et al., 2020
eye efna3b expression absent, abnormal	pax6b^{tq253a/tq253a}; pax6a^ka709/ka709	standard conditions	Fig 8 from Takamiya et al., 2020
eye efnb2a expression absent, abnormal	pax6b^{tq253a/tq253a}; pax6a^ka709/ka709	standard conditions	Fig 8 from Takamiya et al., 2020
eye plxna4 expression decreased amount, abnormal	pax6b^{tq253a/tq253a}; pax6a^ka709/ka709	standard conditions	Fig 8 from Takamiya et al., 2020
eye distal region nrp2b expression absent, abnormal	pax6b^{tq253a/tq253a}; pax6a^ka709/ka709	standard conditions	Fig 8 from Takamiya et al., 2020

Citations