CRISPR

CRISPR3-nr3c1

ID

ZDB-CRISPR-201102-4

Name

CRISPR3-nr3c1

Previous Names

None

Target

nr3c1 (1)

Sequence

5' - CTGCCACATCGTCAGCTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The PAM site was "TGG" at the 3' end.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sh543	nr3c1

Expression

Gene expression in Wild Types + CRISPR3-nr3c1

No data available

Phenotype

Phenotype resulting from CRISPR3-nr3c1

No data available

Phenotype of all Fish created by or utilizing CRISPR3-nr3c1

Phenotype	Fish	Conditions	Figures
whole organism fkbp5 expression decreased amount, abnormal	nr3c1^sh543/sh543	standard conditions	Fig. 3 from Marchi et al., 2020
adenohypophysis pomca expression increased amount, abnormal	nr3c1^sh543/sh543	standard conditions	Fig. 3 from Marchi et al., 2020
adenohypophysis pomca expression increased amount, abnormal	nr3c1^sh543/sh543	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
whole organism fkbp5 expression decreased amount, abnormal	nr3c1^sh543/sh543	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
adenohypophysis pomca expression increased amount, abnormal	nr3c1^sh543/sh543; sh144Tg	standard conditions	Fig. 4 from Marchi et al., 2020
adenohypophysis pomca expression increased amount, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg	standard conditions	Fig. 4 from Marchi et al., 2020
whole organism vegfab expression increased amount, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg/sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
whole organism vegfab expression increased amount, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg/sh144Tg	standard conditions	Fig. 3 from Marchi et al., 2020
whole organism fkbp5 expression decreased amount, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg/sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
whole organism fkbp5 expression decreased amount, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg/sh144Tg	standard conditions	Fig. 3 from Marchi et al., 2020
whole organism egln3 expression increased amount, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg/sh144Tg	chemical treatment by environment: betamethasone dipropionate	Fig. 3 from Marchi et al., 2020
whole organism hypoxia-inducible factor-1alpha signaling pathway decreased efficacy, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg/sh144Tg	standard conditions	Fig. 6 from Marchi et al., 2020
whole organism egln3 expression increased amount, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg/sh144Tg	standard conditions	Fig. 3 from Marchi et al., 2020
whole organism hypoxia-inducible factor-1alpha signaling pathway decreased efficacy, abnormal	vhl^{hu2117/hu2117}; nr3c1^sh543/sh543; sh144Tg + CRISPR3-nr3c2 + CRISPR4-nr3c2 + CRISPR5-nr3c2 + CRISPR6-nr3c2	standard conditions	Fig. 6 from Marchi et al., 2020

Citations