CRISPR

CRISPR1-vcam1b

ID

ZDB-CRISPR-190416-1

Name

CRISPR1-vcam1b

Previous Names

None

Target

Sequence

5' - AGTGAGACTGCGGTCTCTCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
cas011	vcam1b

Expression

Gene expression in Wild Types + CRISPR1-vcam1b

No data available

Phenotype

Phenotype resulting from CRISPR1-vcam1b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-vcam1b

Phenotype	Fish	Conditions	Figures
caudal hematopoietic tissue granulocyte mpx expression decreased amount, abnormal	vcam1b^{cas011/cas011}	control	Fig. S7 from Li et al., 2018
caudal hematopoietic tissue erythroid lineage cell hbae1.1 expression decreased amount, abnormal	vcam1b^{cas011/cas011}	control	Fig. S7 from Li et al., 2018
caudal hematopoietic tissue hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal	vcam1b^{cas011/cas011}	control	Fig. S7 from Li et al., 2018
caudal hematopoietic tissue macrophage lyz expression decreased amount, abnormal	vcam1b^{cas011/cas011}	control	Fig. S7 from Li et al., 2018
hematopoietic stem cell maintenance of location decreased occurrence, abnormal	vcam1b^{cas011/cas011}	control	Fig. 2 from Li et al., 2018
caudal hematopoietic tissue macrophage Ab1-vcam1 labeling absent, abnormal	vcam1b^{cas011/cas011}; zn1Tg	control	Fig. 3 from Li et al., 2018

Citations