CRISPR

CRISPR6-myd88

ID

ZDB-CRISPR-180329-1

Name

CRISPR6-myd88

Previous Names

None

Target

Sequence

5' - GAAAGAAACTGGGTCTGTTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
b1354	myd88

Expression

Gene expression in Wild Types + CRISPR6-myd88

No data available

Phenotype

Phenotype resulting from CRISPR6-myd88

No data available

Phenotype of all Fish created by or utilizing CRISPR6-myd88

Phenotype	Fish	Conditions	Figures
whole organism il1b expression increased amount, abnormal	myd88^b1354/b1354 (AB/TU)	chemical treatment by injection: lipopolysaccharide	Fig. 5 from Loes et al., 2021
whole organism mmp9 expression increased amount, abnormal	myd88^b1354/b1354 (AB/TU)	chemical treatment by injection: lipopolysaccharide	Fig. 5 from Loes et al., 2021
whole organism il1b expression decreased amount, abnormal	myd88^b1354/b1354 (AB/TU)	control	Fig. 5 from Loes et al., 2021
intestine neutrophil decreased amount, abnormal	myd88^b1354/b1354 (AB/TU)	standard conditions	Fig. S1 from Burns et al., 2017
whole organism dead, abnormal	myd88^b1354/b1354 (AB/TU)	chemical treatment by injection: lipopolysaccharide	Fig. 6 from Loes et al., 2021
whole organism mmp9 expression decreased amount, abnormal	myd88^b1354/b1354 (AB/TU)	control	Fig. 5 from Loes et al., 2021
whole organism increased life span, abnormal	myd88^b1354/b1354 (AB/TU)	chemical treatment by injection: lipopolysaccharide	Fig. 6 from Loes et al., 2021

Citations