CRISPR

CRISPR2-lepr

ID
ZDB-CRISPR-160816-3
Name
CRISPR2-lepr
Previous Names
None
Target
Sequence
5' - GGAGCGCCAGTAAAGCCGTGTGG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
nz303 lepr
Expression
Gene expression in Wild Types + CRISPR2-lepr
No data available
Phenotype
Phenotype resulting from CRISPR2-lepr
Phenotype of all Fish created by or utilizing CRISPR2-lepr
Phenotype Fish Conditions Figures
glucose homeostasis decreased process quality, abnormal leprnz303/nz303 (AB) nutrient increased Fig. 2 with image from Kamstra et al., 2022
whole organism increased length, abnormal leprnz303/nz303 (AB) nutrient increased Fig. 2 with image from Kamstra et al., 2022
glucose homeostasis decreased process quality, abnormal leprnz303/nz303 (AB) chemical treatment by injection: Leptin Fig. 4 with image from Kamstra et al., 2022
whole organism increased mass, abnormal leprnz303/nz303 (AB) nutrient increased Fig. 2 with image from Kamstra et al., 2022
blood glucose increased amount, abnormal leprnz303/nz303 (AB) chemical treatment by injection: Leptin, chemical treatment by environment: glucose Fig. 1 with image from Kamstra et al., 2022
glucose homeostasis process quality, ameliorated leprnz303/nz303 (AB) chemical treatment by environment: lithium chloride Fig. 4 with image from Kamstra et al., 2022
glucose homeostasis process quality, ameliorated leprnz303/nz303 (AB) chemical treatment by injection: Leptin, chemical treatment by environment: lithium chloride Fig. 4 with image from Kamstra et al., 2022
blood glucose increased amount, abnormal leprnz303/nz303 (AB) nutrient increased Fig. 2 with image from Kamstra et al., 2022
blood glucose increased amount, abnormal leprnz303/nz303 (AB) chemical treatment by environment: glucose Fig. 1 with image from Kamstra et al., 2022
glucose homeostasis decreased process quality, abnormal leprnz303/nz303 (AB) control Fig. 2 with imageFig. 4 with image from Kamstra et al., 2022
glucose homeostasis decreased process quality, abnormal leprnz303/nz303 (AB) chemical treatment by environment: glucose Fig. 1 with image from Kamstra et al., 2022
glucose homeostasis decreased process quality, abnormal leprnz303/nz303 (AB) chemical treatment by injection: Leptin, chemical treatment by environment: glucose Fig. 1 with image from Kamstra et al., 2022
hypothalamus mCherry expression amount, ameliorated ia5Tg + CRISPR2-lepr chemical treatment by injection: Leptin Fig. 3 with image from Kamstra et al., 2022
heart mCherry expression increased amount, abnormal ia5Tg + CRISPR2-lepr chemical treatment by environment: lithium chloride Fig. 3 with image from Kamstra et al., 2022
hypothalamus mCherry expression increased amount, abnormal ia5Tg + CRISPR2-lepr chemical treatment by environment: lithium chloride Fig. 3 with image from Kamstra et al., 2022
heart canonical Wnt signaling pathway increased process quality, abnormal ia5Tg + CRISPR2-lepr chemical treatment by environment: lithium chloride Fig. 3 with image from Kamstra et al., 2022
hypothalamus canonical Wnt signaling pathway increased process quality, abnormal ia5Tg + CRISPR2-lepr chemical treatment by environment: lithium chloride Fig. 3 with image from Kamstra et al., 2022
hypothalamus canonical Wnt signaling pathway process quality, ameliorated ia5Tg + CRISPR2-lepr chemical treatment by injection: Leptin Fig. 3 with image from Kamstra et al., 2022
pancreas has extra parts of type pancreatic B cell, abnormal vu513Tg + CRISPR2-lepr standard conditions Fig. 3 with image from Michel et al., 2016
Citations