- Title
-
Fucoidan But Not 2'-Fucosyllactose Inhibits Human Norovirus Replication in Zebrafish Larvae
- Authors
- Tan, M.T.H., Li, Y., Eshaghi Gorji, M., Gong, Z., Li, D.
- Source
- Full text @ Viruses
Percentage (%) of norovirus (NoV) GII.4 virus-like particles (VLPs) pre-incubated with fucoidan, 2′-Fucosyllactose (2′-FL) or human milk binding to type A saliva (OD450) in comparison to positive control (NoV GII.4 VLPs without carbohydrate blocking). Each column represents the average of triplicates, and each error bar indicates the standard deviations. |
Detection of human norovirus (hNoV) GII.P16-GII.4 with and without pre-incubation with fucoidan or 2′-Fucosyllactose (2′-FL) from zebrafish larva at 0 and 2 dpi. Each sample contains a pool of 10 larvae. Each column represents the average of four independent experiments conducted in four different weeks, and each error bar indicates the standard deviations. * Below the limit of detection (1.3 log genome copies/sample). ** Two out of three samples were below the limit of detection. |