Lab
Drummond Lab
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Statement of Research Interest
The zebrafish pronephros as a model of kidney development.
We are studying the zebrafish pronephros in order to answer questions concerning early patterning events affecting kidney
development, epithelial cell differentiation, the generation of cell polarity, and the development of kidney vasculature. The
zebrafish pronephric kidney provides a simplified model of nephron development and epithelial cell differentiation which is
amenable to genetic analysis. By taking advantage of mutations affecting the pronephros, we are uncovering new aspects of
kidney cell differentiation.
We are studying the zebrafish pronephros in order to answer questions concerning early patterning events affecting kidney
development, epithelial cell differentiation, the generation of cell polarity, and the development of kidney vasculature. The
zebrafish pronephric kidney provides a simplified model of nephron development and epithelial cell differentiation which is
amenable to genetic analysis. By taking advantage of mutations affecting the pronephros, we are uncovering new aspects of
kidney cell differentiation.
Lab Members
| Liu, Yan Research Staff | Hellman, Nathan | Pathak, Naremdra |