Lab
The ZMNH/Hamburg Zebrafish Lab
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Statement of Research Interest
*** This lab is no longer in existence and Dr. Bernhardt is no longer involved in zebrafish research ***
Our group is interested in the molecular bases of axonal outgrowth during development and regeneration. The focus is on the role of cell adhesion/cell recognition molecules. Our studies combine both molecular and anatomical approaches.
Ongoing projects address the role of extracellular matrix components, of two zebrafish L1 homologs, and of a zebrafish semaphorin (sema z1b) in axon guidance during embryonic development. We are also investigating the roles of these molecules during successful regeneration of the adult retinotectal projection. Using a spinal lesion model, we examine the hypothesis that some of these molecules may contribute to differences in the regenerative competence of different classes of neurons in the adult CNS.
Our group is interested in the molecular bases of axonal outgrowth during development and regeneration. The focus is on the role of cell adhesion/cell recognition molecules. Our studies combine both molecular and anatomical approaches.
Ongoing projects address the role of extracellular matrix components, of two zebrafish L1 homologs, and of a zebrafish semaphorin (sema z1b) in axon guidance during embryonic development. We are also investigating the roles of these molecules during successful regeneration of the adult retinotectal projection. Using a spinal lesion model, we examine the hypothesis that some of these molecules may contribute to differences in the regenerative competence of different classes of neurons in the adult CNS.
Lab Members