Longhou Fang Lab

The Fang lab employ zebrafish and mouse models to studying lipid metabolism in angiogenesis, lymphangiogenesis, and hematopoiesis. During his postdoctoral studies at UC San Diego, Dr. Fang discovered that apolipoprotein (apoA-I) binding protein (AIBP) controls angiogenesis via regulation of cholesterol homeostasis. Based upon the findings, the Fang laboratory will be focusing on the role of AIBP-regulated lipid metabolism in endothelial cell biology. We will use a plethora of developmental and disease models such as zebrafish angiogenesis, murine angiogenesis, heart hypertrophy, heart ischemia and reperfusion, peripheral artery ischemia and reperfusion, corneal angiogenesis, and tumorigenesis in mice.