Lab
Wehner Lab
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Statement of Research Interest
Using zebrafish as model system, our research addresses the question: why are some vertebrates able to regenerate their spinal cord after injury?
Spinal cord injury in mammals leads to life-long paralysis because the severed axons fail to regrow across the site of lesion. In contrast, zebrafish exhibit robust axonal regrowth after injury, leading to substantial recovery of locomotor function. Our research aims to elucidate the cellular and molecular mechanisms underlying the astounding capacity of zebrafish to functionally repair severed axonal connections.
Spinal cord injury in mammals leads to life-long paralysis because the severed axons fail to regrow across the site of lesion. In contrast, zebrafish exhibit robust axonal regrowth after injury, leading to substantial recovery of locomotor function. Our research aims to elucidate the cellular and molecular mechanisms underlying the astounding capacity of zebrafish to functionally repair severed axonal connections.
Lab Members
| Kolb, Julia Graduate Student | Böhm, Benjamin Research Staff |