Brennan Lab

During development of a vertebrate embryo a series of inductive interactions and cellular rearrangements establish the body plan. One process that is critical for proper organisation of the body is segmentation of the mesoderm. My laboratory is studying cellular and molecular mechanisms underlying segmentation and differentiation of the mesoderm with an emphasis on cell-cell signalling by members of the Eph family of receptor tyrosine kinases and other signalling molecules such as calcium.