| Phenotype: | substrate-dependent cell migration, cell attachment to substrate disrupted, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | substrate-dependent cell migration, cell attachment to substrate |
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| Synonyms: | substrate-bound cell migration, cell attachment to substrate |
| Definition: | The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions. |
| Ontology: | GO: Biological Process [GO:0006931] QuickGO AmiGO |
| Name: | disrupted |
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| Synonyms: | |
| Definition: | A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001507] |