| Phenotype: | Wnt signaling pathway, planar cell polarity pathway decreased process quality, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | Wnt signaling pathway, planar cell polarity pathway |
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| Synonyms: | PCP pathway, planar cell polarity pathway, Wnt receptor signaling pathway, planar cell polarity pathway, Wnt receptor signalling pathway, planar cell polarity pathway, Wnt-activated signaling pathway, planar cell polarity pathway, Wnt-JNK signaling pathway, Wnt-PCP signaling pathway |
| Definition: | A type of non-canonical Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the activation small G proteins such as Rho, Rac, and Cdc42 which, in turn activate effectors, including C-Jun N-terminal kinase (JNK) and Rho kinase (Rok). The signaling ends with change in the transcription of target genes and/or reorganisation of the cytoskeleton. |
| Ontology: | GO: Biological Process [GO:0060071] QuickGO AmiGO |
| Name: | decreased process quality |
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| Synonyms: | |
| Definition: | A quality of a process that has a value that is decreased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002302] |