| Phenotype: | liver nucleolus Ab5-chek1 labeling increased amount, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | liver |
|---|---|
| Synonyms: | |
| Definition: | Solid compound organ with three lobes that has many functions including bile production, blood detoxification, the production of critical plasma proteins and clotting factors, complement proteins and the storage of many substances, such as lipids, amino acids, iron, and glycogen. Female fish produce vitellogenins in the liver. |
| Ontology: | Anatomy Ontology [ZFA:0000123] |
| Name: | nucleolus |
|---|---|
| Synonyms: | |
| Definition: | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| Ontology: | GO: Cellular Component [GO:0005730] QuickGO AmiGO |
ANTIBODY LABELING:
EXPRESSION QUALITY:
| Name: | increased amount |
|---|---|
| Synonyms: | accessory, increased, increased number, present in greater numbers in organism, supernumerary |
| Definition: | An amount which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000470] |