Phenotype: | primary motor neuron isl1a expression decreased amount, abnormal |
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Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
Name: | primary motor neuron |
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Synonyms: | primary motoneuron |
Definition: | Motor neurons that arise during the first day of development. Primary motoneurons have larger diameter cell bodies and axons than secondary motoneurons and are positioned more dorsally and medially than secondary motoneurons. Primary motoneurons are present in a single bilateral pair of clusters in each spinal segment and innervate axial muscle fibers in the corresponding pair of myotomes. Axons make a conspicuous loop around the Mauthner axon before entering the ventral root. |
Ontology: | Anatomy Ontology [ZFA:0009244] |
EXPRESSED GENE:
Symbol: | isl1a | ||||||
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Name: | ISL LIM homeobox 1a | ||||||
Previous Names: | Isl-1 (1), isl1, islet-1 | ||||||
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Location: | Chr: 5 Mapping Details/Browsers |
EXPRESSION QUALITY:
Name: | decreased amount |
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Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
Definition: | An amount which is relatively low. |
Ontology: | Phenotypic Quality Ontology [PATO:0001997] |