| Phenotype: | otic vesicle epithelial to mesenchymal transition decreased occurrence, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | otic vesicle |
|---|---|
| Synonyms: | otic capsule, otocyst, ov |
| Definition: | Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells. (Also see Anatomical Atlas entry for ear by T. Whitfield.) |
| Ontology: | Anatomy Ontology [ZFA:0000051] |
| Name: | epithelial to mesenchymal transition |
|---|---|
| Synonyms: | EMT, epithelial-mesenchymal transition, mesenchymal cell differentiation from epithelial cell |
| Definition: | A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. |
| Ontology: | GO: Biological Process [GO:0001837] QuickGO AmiGO |
| Name: | decreased occurrence |
|---|---|
| Synonyms: | decreased incidence |
| Definition: | An occurrence which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002052] |