| Phenotype: | retinal pigmented epithelium pigment granule decreased amount, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | retinal pigmented epithelium |
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| Synonyms: | pigmented epithelium, pigmented retina, pigmented retinal epithelium, PRE, RPE |
| Definition: | A monolayer of pigmented epithelium covering the neural retina; develops from the outer of the two layers of the optic cup. |
| Ontology: | Anatomy Ontology [ZFA:0000144] |
| Name: | pigment granule |
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| Synonyms: | |
| Definition: | A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. |
| Ontology: | GO: Cellular Component [GO:0048770] QuickGO AmiGO |
| Name: | decreased amount |
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| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |