| Phenotype: | testis Sertoli cell amh expression absent, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | testis |
|---|---|
| Synonyms: | testes |
| Definition: | Male reproductive organ. Adult zebrafish testes are paired organs forming elongated structures, internally organized into tubules. These tubules are formed by seminiferous epithelium containing cysts of spermatogonia and spermatocytes surrounded by somatic support cells, called Sertoli cells. Cysts are arranged around a lumen containing spermatozoa that is connected to the efferent ducts. The interstitial regions between the tubules contain the steroid-producing Leydig cells, connective tissue, and blood vessels. |
| Ontology: | Anatomy Ontology [ZFA:0000598] |
| Name: | Sertoli cell |
|---|---|
| Synonyms: | Sertoli cells |
| Definition: | A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier. |
| Ontology: | Anatomy Ontology [ZFA:0009133] |
EXPRESSED GENE:
| Symbol: | amh |
|---|---|
| Name: | anti-Mullerian hormone |
| Location: | Chr: 22 Mapping Details/Browsers |
EXPRESSION QUALITY:
| Name: | absent |
|---|---|
| Synonyms: | absence, absent from organism |
| Definition: | A quality denoting the lack of an entity. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000462] |