| Phenotype: | ovary granulosa cell cyp19a1a expression absent, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | ovary |
|---|---|
| Synonyms: | ovaries |
| Definition: | Female reproductive organ. The ovary is a bilobed cavitated organ located ventral to the swim bladder. |
| Ontology: | Anatomy Ontology [ZFA:0000403] |
| Name: | granulosa cell |
|---|---|
| Synonyms: | granulosa cells |
| Definition: | A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. |
| Ontology: | Anatomy Ontology [ZFA:0009227] |
EXPRESSED GENE:
| Symbol: | cyp19a1a | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Name: | cytochrome P450, family 19, subfamily A, polypeptide 1a | ||||||||||||
| Previous Names: | ar1, cyp19, CYP19a1 (1), cyp19a (1), cypXIX, aromatase, etID309862.18 (1), ovarian aromatase (1), P450aromA (1), zgc:136541 (1) | ||||||||||||
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| Location: | Chr: 18 Mapping Details/Browsers | ||||||||||||
EXPRESSION QUALITY:
| Name: | absent |
|---|---|
| Synonyms: | absence, absent from organism |
| Definition: | A quality denoting the lack of an entity. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000462] |