| Phenotype: | dorsal aorta hematopoietic stem cell runx1 expression decreased amount, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | dorsal aorta |
|---|---|
| Synonyms: | DA, dorsal aortic root |
| Definition: | Principal unpaired, median artery of the trunk, leading from the paired roots (radices) of the dorsal aorta to the caudal artery. |
| Ontology: | Anatomy Ontology [ZFA:0000014] |
| Name: | hematopoietic stem cell |
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| Synonyms: | colony forming unit hematopoietic, hematopoietic progenitor cell, hemopoietic progenitor cell, hemopoietic stem cell, HSC |
| Definition: | A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. |
| Ontology: | Anatomy Ontology [ZFA:0009014] |
EXPRESSED GENE:
| Symbol: | runx1 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Name: | RUNX family transcription factor 1 | ||||||||||||
| Previous Names: | runx1a (1), runxa, aml1 (1) | ||||||||||||
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| Location: | Chr: 1 Mapping Details/Browsers | ||||||||||||
EXPRESSION QUALITY:
| Name: | decreased amount |
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| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |