| Phenotype: | central nervous system glial cell (sensu Vertebrata) olig2 expression decreased amount, abnormal |
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| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | central nervous system |
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| Synonyms: | cns |
| Definition: | The brain and spinal cord. |
| Ontology: | Anatomy Ontology [ZFA:0000012] |
| Name: | glial cell (sensu Vertebrata) |
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| Synonyms: | glial cells (sensu Vertebrata) |
| Definition: | A non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. |
| Ontology: | Anatomy Ontology [ZFA:0009147] |
EXPRESSED GENE:
| Symbol: | olig2 | ||||||||||||
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| Name: | oligodendrocyte lineage transcription factor 2 | ||||||||||||
| Previous Name: | wu:fc64g09 | ||||||||||||
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| Location: | Chr: 9 Mapping Details/Browsers | ||||||||||||
EXPRESSION QUALITY:
| Name: | decreased amount |
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| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |