Phenotype: | endoplasmic reticulum unfolded protein response increased occurrence, abnormal |
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Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
Name: | endoplasmic reticulum unfolded protein response |
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Synonyms: | ER unfolded protein response, erUPR, SREBP-mediated signalling pathway |
Definition: | The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. |
Ontology: | GO: Biological Process [GO:0030968] QuickGO AmiGO |
Name: | increased occurrence |
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Synonyms: | increased incidence |
Definition: | An occurrence which is relatively high. |
Ontology: | Phenotypic Quality Ontology [PATO:0002051] |