| Phenotype: | brain ceramide increased amount, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | brain |
|---|---|
| Synonyms: | brain structure |
| Definition: | Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system. |
| Ontology: | Anatomy Ontology [ZFA:0000008] |
| Name: | ceramide |
|---|---|
| Synonyms: | a ceramide, Cer, Ceramide, ceramides, N-acylated sphingoid |
| Definition: | Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H. |
| Ontology: | ChEBI [CHEBI:17761] ( EBI ) |
| Name: | increased amount |
|---|---|
| Synonyms: | accessory, increased, increased number, present in greater numbers in organism, supernumerary |
| Definition: | An amount which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000470] |