ZFIN Phenotype Statement: atrioventricular valve canonical Wnt signaling pathway involved in heart development process quality, abnormal

Phenotype:	atrioventricular valve canonical Wnt signaling pathway involved in heart development process quality, abnormal
Note:	This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.

Name:	atrioventricular valve
Synonyms:
Definition:	The atrioventricular valve has four distinct leaflets oriented anterior, posterior, left, and right of the atrioventricular orifice.
Ontology:	Anatomy Ontology [ZFA:0005064]

Name:	canonical Wnt signaling pathway involved in heart development
Synonyms:	canonical Wnt receptor signaling pathway involved in heart development, canonical Wnt receptor signalling pathway involved in heart development, canonical Wnt-activated signaling pathway involved in heart development
Definition:	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Ontology:	GO: Biological Process [GO:0061316] QuickGO AmiGO

Name:	process quality
Synonyms:	quality of a process, quality of occurrent, quality of process, relational quality of occurrent
Definition:	A quality which inheres in an process.
Ontology:	Phenotypic Quality Ontology [PATO:0001236]