ZFIN Phenotype Statement: bulbus arteriosus canonical Wnt signaling pathway involved in heart development decreased occurrence, abnormal

Phenotype:	bulbus arteriosus canonical Wnt signaling pathway involved in heart development decreased occurrence, abnormal
Note:	This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.

Name:	bulbus arteriosus
Synonyms:	cardiac outflow tract, outflow tract, truncus
Definition:	Multi-tissue structure that consists of three layers and through which the blood exits the heart. The bulbus arteriosus is a pear shaped chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches.
Ontology:	Anatomy Ontology [ZFA:0000173]

Name:	canonical Wnt signaling pathway involved in heart development
Synonyms:	canonical Wnt receptor signaling pathway involved in heart development, canonical Wnt receptor signalling pathway involved in heart development, canonical Wnt-activated signaling pathway involved in heart development
Definition:	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Ontology:	GO: Biological Process [GO:0061316] QuickGO AmiGO

Name:	decreased occurrence
Synonyms:	decreased incidence
Definition:	An occurrence which is relatively low.
Ontology:	Phenotypic Quality Ontology [PATO:0002052]