Phenotype: translation decreased efficacy, abnormal
Note: This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.
Name: translation
Synonyms: protein anabolism, protein biosynthesis, protein biosynthetic process, protein formation, protein synthesis, protein translation
Definition: The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
Ontology: GO: Biological Process [GO:0006412]    QuickGO    AmiGO
Name: decreased efficacy
Synonyms:
Definition: A decrease in the ability of a process to produce its output.
Ontology: Phenotypic Quality Ontology [PATO:0015003]