| Phenotype: | proliferative region intrinsic apoptotic signaling pathway by p53 class mediator increased occurrence, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | proliferative region |
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| Synonyms: | cell cycle, cell division, proliferation |
| Definition: | Anatomical cluster which consists of rapidly dividing cells. |
| Ontology: | Anatomy Ontology [ZFA:0000098] |
| Name: | intrinsic apoptotic signaling pathway by p53 class mediator |
|---|---|
| Synonyms: | intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator, signal transduction by p53 class mediator resulting in induction of apoptosis |
| Definition: | The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered. |
| Ontology: | GO: Biological Process [GO:0072332] QuickGO AmiGO |
| Name: | increased occurrence |
|---|---|
| Synonyms: | increased incidence |
| Definition: | An occurrence which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002051] |