| Phenotype: | Mauthner neuron chemical synaptic transmission increased frequency, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | Mauthner neuron |
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| Synonyms: | |
| Definition: | Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon. |
| Ontology: | Anatomy Ontology [ZFA:0009149] |
| Name: | chemical synaptic transmission |
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| Synonyms: | neurotransmission, regulation of synapse, signal transmission across a synapse, synaptic transmission |
| Definition: | The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. |
| Ontology: | GO: Biological Process [GO:0007268] QuickGO AmiGO |
| Name: | increased frequency |
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| Synonyms: | frequent, high frequency |
| Definition: | A frequency which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000380] |