| Phenotype: | caudal vein plexus sprouting angiogenesis decreased occurrence, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | caudal vein plexus |
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| Synonyms: | |
| Definition: | Post-vent vasculature which forms an interconnecting network of venous tubes. The caudal vein plexus forms via a very active period of angiogenic sprouting, beginning at 25 hpf when venous endothelial cells of the posterior cardinal vein sprout and migrate ventrally, then fuse with neighboring tip cells. This process reiterates during a five-hour window, forming a primordial plexus by 30 hpf. By two days of development, the primitive caudal vein plexus has matured into a complex, well-perfused, venous vascular network. Starting at 4 dpf the caudal vein plexus starts to remodel and simplify. |
| Ontology: | Anatomy Ontology [ZFA:0001286] |
| Name: | sprouting angiogenesis |
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| Synonyms: | |
| Definition: | The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation. |
| Ontology: | GO: Biological Process [GO:0002040] QuickGO AmiGO |
| Name: | decreased occurrence |
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| Synonyms: | decreased incidence |
| Definition: | An occurrence which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002052] |