| Phenotype: | spinal cord central nervous system myelination decreased process quality, exacerbated |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | spinal cord |
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| Synonyms: | medulla spinalis, spinal cord structure |
| Definition: | |
| Ontology: | Anatomy Ontology [ZFA:0000075] |
| Name: | central nervous system myelination |
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| Synonyms: | myelination in central nervous system |
| Definition: | The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. |
| Ontology: | GO: Biological Process [GO:0022010] QuickGO AmiGO |
| Name: | decreased process quality |
|---|---|
| Synonyms: | |
| Definition: | A quality of a process that has a value that is decreased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002302] |
| Tag: | exacerbated |
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| Definition: | This annotation denotes a significantly exaggerated phenotype resulting from an additional reagent or mutation. |