| Phenotype: | dorsal habenular nucleus chemical synaptic transmission decreased process quality, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | dorsal habenular nucleus |
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| Synonyms: | dorsal habenular nuclei, dorsal nuclei |
| Definition: | Habenular nucleus where the efferent projections innervate the interpeduncular nucleus. The dorsal habenula is structurally homologous to the mammalian medial habenula. |
| Ontology: | Anatomy Ontology [ZFA:0000197] |
| Name: | chemical synaptic transmission |
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| Synonyms: | neurotransmission, regulation of synapse, signal transmission across a synapse, synaptic transmission |
| Definition: | The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. |
| Ontology: | GO: Biological Process [GO:0007268] QuickGO AmiGO |
| Name: | decreased process quality |
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| Synonyms: | |
| Definition: | A quality of a process that has a value that is decreased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002302] |