| Phenotype: | epidermal cell desmosome malformed, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | epidermal cell |
|---|---|
| Synonyms: | epidermal cells |
| Definition: | A cell found in the outermost layer of the organism. |
| Ontology: | Anatomy Ontology [ZFA:0009183] |
| Name: | desmosome |
|---|---|
| Synonyms: | macula adherens, spot desmosome |
| Definition: | A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. |
| Ontology: | GO: Cellular Component [GO:0030057] QuickGO AmiGO |
| Name: | malformed |
|---|---|
| Synonyms: | malformation |
| Definition: | A morphological quality inhering in a bearer by virtue of the bearer's being distorted during formation. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000646] |