ZFIN Phenotype Statement: Mauthner neuron axon initial segment kcna1a expression decreased amount, abnormal

Phenotype:	Mauthner neuron axon initial segment kcna1a expression decreased amount, abnormal
Note:	This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality.

EXPRESSION ANATOMY:

Name:	Mauthner neuron
Synonyms:
Definition:	Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon.
Ontology:	Anatomy Ontology [ZFA:0009149]

Name:	axon initial segment
Synonyms:	initial segment
Definition:	Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
Ontology:	GO: Cellular Component [GO:0043194] QuickGO AmiGO

EXPRESSED GENE:

Symbol:

Name:

potassium voltage-gated channel, shaker-related subfamily, member 1a

Previous Names:

kcna1, Kv1.1 (1), G62942 (1), Kv1.1b (1), si:ch73-333m22.1 (1), wu:fa27a01

Location:

Chr: 25 Mapping Details/Browsers

EXPRESSION QUALITY:

Name:	decreased amount
Synonyms:	decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary
Definition:	An amount which is relatively low.
Ontology:	Phenotypic Quality Ontology [PATO:0001997]