| Phenotype: | renal glomerulus glomerular basement membrane accumulation glomerular basement membrane extracellular matrix, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | renal glomerulus |
|---|---|
| Synonyms: | glomerular capillary tuft, renal glomeruli |
| Definition: | The multi-tissue structure where the glomerular basement membrane supported by mesonephric podocytes, filters blood from the glomerular capillaries. |
| Ontology: | Anatomy Ontology [ZFA:0001288] |
| Name: | glomerular basement membrane |
|---|---|
| Synonyms: | glomerular filtration membrane |
| Definition: | Membrane between the mesonephric podocytes and the renal glomerular capillaries. It is a trilaminar structure composed of the fused basement membranes of the glomerular capillaries and basement membrane of the podocytes. The capillary membranes touch the GBM at contact points that are separated by pores. The membrane is semi-permeable allowing water and small molecules to pass into the renal capsular space. |
| Ontology: | Anatomy Ontology [ZFA:0005285] |
| Name: | accumulation |
|---|---|
| Synonyms: | pooled |
| Definition: | A structural quality of the collection or massing of one physical object within another physical object. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002269] |
| Name: | extracellular matrix |
|---|---|
| Synonyms: | matrisome, proteinaceous extracellular matrix |
| Definition: | A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. |
| Ontology: | GO: Cellular Component [GO:0031012] QuickGO AmiGO |