| Phenotype: | optic cup anatomical region has fewer parts of type neural crest cell, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | optic cup |
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| Synonyms: | eye cup |
| Definition: | Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye. |
| Ontology: | Anatomy Ontology [ZFA:0001202] |
| Name: | anatomical region |
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| Synonyms: | |
| Definition: | A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm. |
| Ontology: | Spatial Ontology [BSPO:0000070] |
| Name: | has fewer parts of type |
|---|---|
| Synonyms: | decreased number of, has decreased number of, has fewer physical parts of type |
| Definition: | The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002001] |
| Name: | neural crest cell |
|---|---|
| Synonyms: | neural crest cells |
| Definition: | A cell of the neural crest. The neural crest is a strip of specialized ectoderm, the neural plate border, which flanks each side of the embryonic neural plate. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesenchymal transition and delamination to form migratory neural crest cells. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells. |
| Ontology: | Anatomy Ontology [ZFA:0009165] |