| Phenotype: | intestinal epithelium desmosome decreased distribution, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | intestinal epithelium |
|---|---|
| Synonyms: | intestine epithelium, villous epithelium |
| Definition: | Simple columnar epithelium that lines the intestine, sometimes pseudostratified, with absorptive brush-border cells and mucous goblet cells clearly visible. |
| Ontology: | Anatomy Ontology [ZFA:0005124] |
| Name: | desmosome |
|---|---|
| Synonyms: | macula adherens, spot desmosome |
| Definition: | A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. |
| Ontology: | GO: Cellular Component [GO:0030057] QuickGO AmiGO |
| Name: | decreased distribution |
|---|---|
| Synonyms: | low distribution |
| Definition: | A distribution which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001672] |